abstract：OBJECTIVE:To characterize acute (postprandial) and chronic (after a 6-month period of weight loss) effects of a low-carbohydrate vs. a low-fat diet on subclinical markers of cardiovascular disease (CVD) in adults with type 2 diabetes. DESIGN:At baseline and 6 months, measures of C-reactive protein (CRP), interleukin-6...

journal_title：Journal of diabetes and its complications

authors： Davis NJ,Crandall JP,Gajavelli S,Berman JW,Tomuta N,Wylie-Rosett J,Katz SD

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:In diabetes, foot ulceration may result from increased skin fragility. Retinoids can reverse some diabetes-induced deficits of skin structure and function, but their clinical utility is limited by skin irritation. The effects of diabetes and MDI 301, a nonirritating synthetic retinoid, and retinoic acid have...

journal_title：Journal of diabetes and its complications

authors： Zeng W,Tahrani A,Shakher J,Varani J,Hughes S,Dubb K,Stevens MJ

更新日期：2011-11-01 00:00:00

abstract：PURPOSE:To evaluate the effect of glucose regulation on intravitreal ranibizumab injection for clinically significant diabetic macular edema (DME). METHODS:This retrospective study enrolled 65 eyes of 65 patients with persistent DME treated with intravitreal ranibizumab injection. The main outcome measures were the ch...

journal_title：Journal of diabetes and its complications

authors： Ozturk BT,Kerimoglu H,Adam M,Gunduz K,Okudan S

更新日期：2011-09-01 00:00:00

abstract：UNLABELLED:Controversial data suggest that patients with type 2 diabetes mellitus have an increased risk of fractures despite having, in some studies, higher bone mineral density. METHODS:The aim of this study was to determine the prevalence of osteoporosis and morphometric vertebral fractures in 148 postmenopausal di...

journal_title：Journal of diabetes and its complications

authors： Viégas M,Costa C,Lopes A,Griz L,Medeiro MA,Bandeira F

更新日期：2011-07-01 00:00:00

abstract：AIMS:Using psychological and quality of life assessment tools, we prospectively studied changes in health-related quality of life and emotional well-being in patients who had commenced GLP-1 analogue therapy (exenatide) and compared them with new insulin starters. METHODS:Two matched groups of patients with type 2 dia...

journal_title：Journal of diabetes and its complications

authors： Grant P,Lipscomb D,Quin J

更新日期：2011-07-01 00:00:00

abstract：PROBLEM:Depression is associated with a higher risk of macrovascular and microvascular complications and mortality in diabetes, but whether depression is linked to an increased risk of incident amputations is unknown. We examined the association between diagnosed depression and incident non-traumatic lower limb amputat...

journal_title：Journal of diabetes and its complications

authors： Williams LH,Miller DR,Fincke G,Lafrance JP,Etzioni R,Maynard C,Raugi GJ,Reiber GE

更新日期：2011-05-01 00:00:00

abstract：AIM:Analyze clustering of unhealthy lifestyle behavior and its relationship with nonadherence to clinical preventive care services among Spanish diabetic adults. METHODS:Cross-sectional study including 2156 diabetic adults from the 2006 Spanish National Health Survey. Subjects were asked about their uptake of BP measu...

journal_title：Journal of diabetes and its complications

authors： Jiménez-García R,Esteban-Hernández J,Hernández-Barrera V,Jimenez-Trujillo I,López-de-Andrés A,Carrasco Garrido P

更新日期：2011-03-01 00:00:00

abstract：:The purpose of this article is to provide reasons to start looking more critically at the existing glucose-lowering therapies in diabetes, from the point of their effect on cardiac metabolism. The presented arguments begin with the description of major differences between metabolism in myocardium and the skeletal musc...

journal_title：Journal of diabetes and its complications

authors： Kolaczynski JW

更新日期：2011-01-01 00:00:00

abstract：PURPOSE:To evaluate the frequency of mutations in the HFE gene (C282Y and H63D) in type 2 diabetes mellitus (DM) patients and their possible association with diabetic chronic complications. METHODS:A case-control study with 723 subjects was performed. All diabetic subjects (n=519) underwent a clinical and laboratory e...

journal_title：Journal of diabetes and its complications

authors： Colli ML,Gross JL,Canani LH

更新日期：2011-01-01 00:00:00

abstract：:Myo-inositol oxygenase (MIOX) is the first and rate-limiting enzyme in myo-inositol (MI) metabolism pathway. The increase in MIOX enzyme activity is in proportion to serum glucose concentrations and may be responsible for the MI depletion found in the diabetic complications. The aim was to investigate whether single n...

journal_title：Journal of diabetes and its complications

authors： Yang B,Hodgkinson A,Millward BA,Demaine AG

更新日期：2010-11-01 00:00:00

abstract：OBJECTIVE:To measure trends in glycemic control in type 2 diabetes in the United States from 1988-1994 to 1999-2004 and to identify factors influencing glycemic control, including the presence of comorbid conditions and race/ethnicity. METHODS:Participants in the National Health and Nutrition Examination Surveys (1988...

journal_title：Journal of diabetes and its complications

authors： Suh DC,Choi IS,Plauschinat C,Kwon J,Baron M

更新日期：2010-11-01 00:00:00

abstract：AIM:To examine the diabetes self-care behaviors of Filipino-American (FA) adults with type 2 diabetes mellitus (DM). METHOD:The Summary of Diabetes Self Care Activities-Revised and Expanded measure was administered to 192 (74 males and 118 females) FA adult immigrants with type 2 DM. RESULTS:Older FAs (> or =65 years...

journal_title：Journal of diabetes and its complications

authors： Jordan DN,Jordan JL

更新日期：2010-07-01 00:00:00

abstract：OBJECTIVE:The notion of combining immunomodulatory agents with the incretin exendin-4 (Ex-4) has seen considerable favor as a potential therapy for the reversal of type 1 diabetes in man. While the addition of Ex-4 provides modest improvement to the effectiveness of immunological-based monotherapies in reversing hyperg...

journal_title：Journal of diabetes and its complications

authors： Xue S,Wasserfall C,Parker M,McGrail S,McGrail K,Campbell-Thompson M,Schatz DA,Atkinson MA,Haller MJ

更新日期：2010-05-01 00:00:00

abstract：OBJECTIVE:To systematically investigate the effect of lack of adherence to the recommended change in insulin pump infusion line use beyond 48 h and determine whether the type of insulin made a difference. RESEARCH DESIGN AND METHODS:This was a double-blind, randomized, crossover trial with 20 patients with diabetes me...

journal_title：Journal of diabetes and its complications

authors： Thethi TK,Rao A,Kawji H,Mallik T,Yau CL,Christians U,Fonseca V

更新日期：2010-03-01 00:00:00

abstract：:There is increasing evidence that glycemic disorders such as rapid glucose fluctuations over a daily period might play an important role on diabetic complications. We evaluated the efficacy of sitagliptin 100 mg once daily vs. vildagliptin 50 mg twice daily on daily blood glucose fluctuations in patients with type 2 d...

journal_title：Journal of diabetes and its complications

authors： Marfella R,Barbieri M,Grella R,Rizzo MR,Nicoletti GF,Paolisso G

更新日期：2010-03-01 00:00:00

abstract：:Diabetic retinopathy resists arrest of its progression after reestablishment of good glycemic control that follows a profound period of poor glycemic control. The objective of this study was to elucidate the role of inflammation in the resistance of retinopathy to arrest after termination of hyperglycemia. Streptozoto...

journal_title：Journal of diabetes and its complications

authors： Chan PS,Kanwar M,Kowluru RA

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:Increased arterial stiffness is a marker of atherosclerosis and is recognised early in the course of type 2 diabetes mellitus (T2DM). Matrix metalloproteinases (MMP) and their tissue inhibitors (TIMP) are a family of proteolytic enzymes which are essential for the structure and function of large arteries. In ...

journal_title：Journal of diabetes and its complications

authors： Papazafiropoulou A,Perrea D,Moyssakis I,Kokkinos A,Katsilambros N,Tentolouris N

更新日期：2010-01-01 00:00:00

abstract：:A 27-year-old male, who had developed diabetes mellitus type 1 (DMT1) since the age of eighteen and alopecia areata universalis nine months later, attended the outpatient clinics complaining of general fatigue and shortness of breath. A Schilling test was indicative of pernicious anemia. Antigastric parietal cell (AGP...

journal_title：Journal of diabetes and its complications

authors： Tzellos TG,Tahmatzidis DK,Lallas A,Apostolidou K,Goulis DG

更新日期：2009-11-01 00:00:00

abstract：AIM OF THE STUDY:The aim of this study was to evaluate reverse volumetric left ventricular (LV) remodeling after cardiac resynchronization therapy (CRT) in patients with heart failure (HF) with vs. without diabetes mellitus (DM). METHODS:The study comprised 130 consecutive patients with HF (mean age, 61+/-12 years) wh...

journal_title：Journal of diabetes and its complications

authors： Soliman OI,van Dalen BM,Theuns DA,ten Cate FJ,Nemes A,Jordaens LJ,Geleijnse ML

更新日期：2009-09-01 00:00:00

abstract：:The aim of this cross-sectional study was to determine the significant limitations, sensitivity, specificity, partial correlations, and odds ratios of nutrient intake in patients with and without hypertension with Type 2 diabetes mellitus. Diabetic patients (n=220) with clinical diagnosis of hypertension and diabetic ...

journal_title：Journal of diabetes and its complications

authors： Celik F,Celik M,Akpolat V

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:There are significant regional variations in prevalence of diabetes and diabetic chronic renal insufficiency (CRI) in India. Oxidative stress plays an important role in the development of diabetic complications. To determine the importance of the polymorphisms in the genes involved in maintenance of cellular...

journal_title：Journal of diabetes and its complications

authors： Tiwari AK,Prasad P,B K T,Kumar KM,Ammini AC,Gupta A,Gupta R

更新日期：2009-03-01 00:00:00

abstract：AIM:Changes in glycoconjugate metabolism during the development of diabetic complications and their modulation by feeding bitter gourd and spent turmeric as fiber-rich source. METHOD:This was studied by measuring the contents of total sugar, uronic acid, amino sugar, and sulfate in the streptozotocin-induced diabetic ...

journal_title：Journal of diabetes and its complications

authors： Vijayalakshmi B,Kumar GS,Salimath PV

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVES:Controversy remains as to the effects of type 2 diabetes on bone metabolism. The aims of this study were to assess the association between type 2 diabetes and bone mineral density (BMD) and to evaluate the possible relationship between chronic diabetic complications and bone density. METHODS:Bone mineral de...

journal_title：Journal of diabetes and its complications

authors： Anaforoglu I,Nar-Demirer A,Bascil-Tutuncu N,Ertorer ME

更新日期：2009-01-01 00:00:00

abstract：:Plasma semicarbazide-sensitive amine oxidase (SSAO) and angiotensin-converting enzyme (ACE) were studied for their correlation with diabetes (DM) complication. The effect of interaction between SSAO and ACE in DM complication is of interest. Studying the functional change due to interaction between SSAO and ACE is dif...

journal_title：Journal of diabetes and its complications

authors： Wiwanitkit V

更新日期：2008-11-01 00:00:00

abstract：:Glycogenic hepatopathy is an underrecognized complication of long-standing poorly controlled diabetes mellitus. It is characterized by abnormal glycogen accumulation in hepatocytes, elevated liver enzymes and hepatomegaly. This is a distinct entity from other causes of hepatomegaly and elevated liver enzymes in diabet...

journal_title：Journal of diabetes and its complications

authors： Hudacko RM,Manoukian AV,Schneider SH,Fyfe B

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVE:This study aimed to determine the prevalence of type 2 diabetes mellitus (DM) and impaired fasting glycemia (IFG), identify their associated factors, determine how the prevalence of type 2 DM has changed over 10 years, and assess the awareness and state of control of diabetes in Jordan. METHODS:Data were ana...

journal_title：Journal of diabetes and its complications

authors： Ajlouni K,Khader YS,Batieha A,Ajlouni H,El-Khateeb M

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:The use of safe iodinated contrast media (CM) to prevent contrast-induced nephropathy (CIN) is an important consideration among renally impaired diabetic patients during coronary angiography. HYPOTHESIS:Diabetic patients with normal or mild renal dysfunction are less likely to receive renal protective measu...

journal_title：Journal of diabetes and its complications

authors： Hardiek KJ,Katholi RE,Robbs RS,Katholi CE

更新日期：2008-05-01 00:00:00

abstract：OBJECTIVES:The objectives of this study were to evaluate and to compare the glycemic control of various antidiabetic agents and the role of homocysteine in type 2 diabetes mellitus. RESEARCH DESIGN AND METHODS:Two hundred forty patients with type 2 diabetes mellitus, divided into Groups 1-6 (n=40), received glipizide,...

journal_title：Journal of diabetes and its complications

authors： Yegnanarayan R,Suryavanshi M,Singh M,Desai S

更新日期：2008-03-01 00:00:00

abstract：:Hyperglycemic syndromes cause disturbances in the tonicity of body fluids, the distribution of body water between major body fluid compartments, and the external balance of body solute and water. The unique feature of dialysis-associated hyperglycemia (DH) is that, during its development, it can cause changes exclusiv...

journal_title：Journal of diabetes and its complications

authors： Tzamaloukas AH,Ing TS,Siamopoulos KC,Rohrscheib M,Elisaf MS,Raj DS,Murata GH

更新日期：2007-11-01 00:00:00

abstract：:Hemoglobin (Hb) A1C is the nonenzymatic glycated product of the Hb beta chain at the valine terminal residue. Recently, the nature of energy-consuming reaction in HbA1C formation was reported, and this was proposed as an underlying pathophysiology for poor nutritional status, muscle loss, and functional impairment in ...

journal_title：Journal of diabetes and its complications

authors： Wiwanitkit V

更新日期：2007-09-01 00:00:00

abstract：AIMS:The objective of this study was to determine whether baseline albuminuria predicts coronary artery calcification (CAC) progression in subjects with type 1 diabetes and whether angiotensin-converting enzyme inhibitor (ACE-I) or angiotensin II type I receptor blocker (ARB) treatment is associated with lower odds of ...

journal_title：Journal of diabetes and its complications

authors： Maahs DM,Snell-Bergeon JK,Kinney GL,Wadwa RP,Garg S,Ogden LG,Rewers M

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:The prevalence of the metabolic syndrome is rapidly increasing with a considerable ethnic variation within and across populations. This study was conducted to estimate the prevalence of the metabolic syndrome and its individual components using Adult Treatment Panel III (ATP III) criteria among Northern Jord...

journal_title：Journal of diabetes and its complications

authors： Khader Y,Bateiha A,El-Khateeb M,Al-Shaikh A,Ajlouni K

更新日期：2007-07-01 00:00:00

abstract：AIM:One putative determinant of diabetic nephropathy is the Pro12Ala (P12A) polymorphism in the gene encoding peroxisome proliferator-activated receptor gamma (PPARgamma). Previous research has found a "protective" role for the A12 allele in association with type 2 diabetes, atherosclerosis, and measures of kidney dama...

journal_title：Journal of diabetes and its complications

authors： Pollex RL,Mamakeesick M,Zinman B,Harris SB,Hegele RA,Hanley AJ

更新日期：2007-05-01 00:00:00

abstract：OBJECTIVES:Metformin is widely used in patients with type 2 diabetes but may decrease vitamin B(12) levels and increase levels of homocysteine (Hcy), a cardiovascular risk factor. Rosiglitazone, a peroxisome proliferator-activated receptor-gamma agonist, may reduce markers of inflammation. We investigated whether 6 wee...

journal_title：Journal of diabetes and its complications

authors： Sahin M,Tutuncu NB,Ertugrul D,Tanaci N,Guvener ND

更新日期：2007-03-01 00:00:00

abstract：OBJECTIVE:Two insulin regimens were used to explore acute and chronic postprandial changes in glycemia, lipemia, and metabolic markers associated with increased risk of cardiovascular disease. METHODS:An open-label, randomized, two-period crossover study (12 weeks/period) compared a prandial regimen [premeal insulin l...

journal_title：Journal of diabetes and its complications

authors： Ceriello A,Del Prato S,Bue-Valleskey J,Beattie S,Gates J,de la Peña A,Malone J

更新日期：2007-01-01 00:00:00

abstract：:The relationship between the effect of aldose reductase inhibitors (ARIs) on the activation of the polyol pathway and on diabetic neuropathy has not been fully established. To address this issue, we investigated the effect of epalrestat (150 mg/day), an ARI, on erythrocyte sorbitol levels as an index of polyol activat...

journal_title：Journal of diabetes and its complications

authors： Ando H,Takamura T,Nagai Y,Kaneko S,Kanazawa University Multicenter Diabetes Study Group.

更新日期：2006-11-01 00:00:00

abstract：:The paraoxonase (PON) gene cluster maps to human chromosome 7q21-22. In the PON 1 gene, several polymorphisms in the promoter and coding regions have been identified and are known to influence gene expression levels. Promoter polymorphisms have been shown to have the strongest influence on paraoxonase activity levels....

journal_title：Journal of diabetes and its complications

authors： Hofer SE,Bennetts B,Chan AK,Holloway B,Karschimkus C,Jenkins AJ,Silink M,Donaghue KC

更新日期：2006-09-01 00:00:00

abstract：:The thickening of alveolar basement membrane is found in autopsies, along with microvascular pathologies, in Type 1 and 2 diabetes mellitus (DM). To detect the function and permeability of alveolar basement membrane, carbon monoxide diffusion capacity (DLCO) and technetium 99m-diethyltriaminepentaaceticacid ((99m)Tc-D...

journal_title：Journal of diabetes and its complications

authors： Ozşahin K,Tuğrul A,Mert S,Yüksel M,Tuğrul G

更新日期：2006-07-01 00:00:00

abstract：OBJECTIVE:There are no large studies in Type 1 diabetic patients that have examined the relation between soluble adhesion molecules and micro- and macrovascular outcomes, although the risks of such complications are high. Therefore, the main objective is to examine the relationship between soluble (s) vascular cell adh...

journal_title：Journal of diabetes and its complications

authors： Soedamah-Muthu SS,Chaturvedi N,Schalkwijk CG,Stehouwer CD,Ebeling P,Fuller JH,EURODIAB Prospective Complications Study group.

更新日期：2006-05-01 00:00:00

abstract：:Since the discovery of the hepatitis C virus (HCV) in 1989, attention has been paid to the association of chronic HCV infection and the development of diabetes. The risk factors for diabetes include older age, HCV genotype 3, severe liver fibrosis, family history of diabetes, and liver/kidney transplantation. Emerging...

journal_title：Journal of diabetes and its complications

authors： Noto H,Raskin P

更新日期：2006-03-01 00:00:00